Saturday, May 18, 2013

Obgyn - Klasifikasi Kanker Serviks



Klasifikasi Kanker Serviks

Jenis histopatologik kanker serviks menurut WHO :
Epithelial
Karsinoma sel skuamosa
Keratin
Nonkeratin
Kondilomatosa
Veruka
Papilaria
Lymphoepithelioma – like carcinoma
Adenokarsinoma
Adenokarsinoma musinosum
Adenokarsinoma endometoid
Adenokarsinoma sel jernih
Adenokarsinoma serosum
Adenokarsinoma mesonefroid
Karsinoma adenoskuamosa
Glassy cell carcinoma
Karsinoma kistik adenoid
Karsinoma basal adenoid
Karsinoid tumor
Karsinoma sel kecil
Karsinoma undifferentiated
Mesenkimal
Sarkoma Stroma endoserviks
Sarkoma botryoides
Sarkoma Stroma endometroid
Alveolar soft-part sarcoma
Leiomiosarkom




Dalam sistem AJCC  ( American Joint Committee on Cancer ), stadium menggunakan angka Romawi 0 s/d IV (0-4). Secara umum, angka yang lebih rendah menunjukkan semakin kecil kemungkinan kanker telah menyebar. Angka yang lebih tinggi, seperti stadium IV (4) menunjukkan kanker yang lebih serius.
  • Stadium 0 (Carsinoma in Situ): Sel-sel kanker serviks hanya ditemukan di lapisan terdalam leher rahim
  • Stadium I: kanker ditemukan pada leher rahim saja.
  • Stadium II: kanker telah menyebar di luar leher rahim tetapi tidak ke dinding panggul atau sepertiga bagian bawah vagina.
  • Stadium III: kanker serviks telah menyebar ke sepertiga bagian bawah vagina, mungkin telah menyebar ke dinding panggul, dan/atau telah menyebabkan ginjal tidak berfungsi
  • Stadium IV: kanker serviks telah menyebar ke kandung kemih, rektum, atau bagian lain dari tubuh (paru-paru, tulang, liver, dll)
FIGO
Deskripsi
TNM

Tumor primer tidak dapat diakses
T x

Tidak ada bukti tumor primer
T 0
0
Karsinoma In Situ ( KIS)
T is
I
Karsinoma terbatas serviks
T 1
I a
Karsinoma hanya dapat didiagnosis secara mikroskopik
T 1 a
I a1
Invasi stroma dalamnya <3 mm dan lebarnya < 7 mm
T 1 a1
I a2
Invasi stroma dalamnya 3-5 mm dan lebarnya < 7 mm
T 1  a2
I b1
Secara klinis lesi < 4 cm
T 1 b1
I b2
Secara klinis lesi > 4 cm
T 1 b2
II
Proses keganasan telah keluar dari serviks dan menjalar 2/3 bagian atas vagina dan parametrium, tetapi tidak sampai dinding panggul
T 2
II a
Penyebaran hanya ke vagina, parametrium masih bebas dari infitrat tumor
T 2a
II b
Penyebaran ke parametrum
T 2b
III
Tumor menginvasi sampai dinding pelvis dan atau menginfiltrasi dampai 1/3 distal vagina dan atau menyebabkan hidronefrosis atau gagal ginjal
T 3
III a
Penyebaran sampai 1/3 bagian distal vagina
T 3a
III b
Penyebaran sudah sampai dinding panggul,
T 3b
IV
Proses keganasan telah keluar dari panggul kecil dan melibatkan mokusa rektum dan atau vesika urinaria atau telah bermetastasi keluar panggul ketempat yang jauh
T 4
IV a
Proses sudah sampai mukosa rektum dan atau vesika urinaria atau sudah keluar dari pangul kecil, metastasi jauh belum terjadi
T 4a
IV b
Telah terjadi metastasi jauh
T 4b
Tabel 1. Staging Karsinoma Serviks Menurut FIGO1
    
 








   

5 comments:

Unknown said...

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Unknown said...

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Utsukushiikirei said...

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Unknown said...

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