Klasifikasi Kanker Serviks
Jenis
histopatologik kanker serviks menurut WHO :
Epithelial
|
|
Karsinoma sel skuamosa
|
Keratin
|
Nonkeratin
|
|
Kondilomatosa
|
|
Veruka
|
|
Papilaria
|
|
Lymphoepithelioma – like carcinoma
|
|
Adenokarsinoma
|
Adenokarsinoma musinosum
|
Adenokarsinoma endometoid
|
|
Adenokarsinoma sel jernih
|
|
Adenokarsinoma serosum
|
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Adenokarsinoma mesonefroid
|
|
Karsinoma adenoskuamosa
|
Glassy cell carcinoma
|
Karsinoma kistik adenoid
|
|
Karsinoma basal adenoid
|
|
Karsinoid tumor
|
|
Karsinoma sel kecil
|
|
Karsinoma undifferentiated
|
Mesenkimal
|
Sarkoma
Stroma endoserviks
Sarkoma
botryoides
Sarkoma
Stroma endometroid
Alveolar
soft-part sarcoma
Leiomiosarkom
|
Dalam
sistem AJCC ( American Joint Committee
on Cancer ), stadium menggunakan angka Romawi 0 s/d IV (0-4). Secara umum,
angka yang lebih rendah menunjukkan semakin kecil kemungkinan kanker telah
menyebar. Angka yang lebih tinggi, seperti stadium IV (4) menunjukkan kanker
yang lebih serius.
- Stadium 0 (Carsinoma in Situ): Sel-sel kanker serviks hanya ditemukan di lapisan terdalam leher rahim
- Stadium I: kanker ditemukan pada leher rahim saja.
- Stadium II: kanker telah menyebar di luar leher rahim tetapi tidak ke dinding panggul atau sepertiga bagian bawah vagina.
- Stadium III: kanker serviks telah menyebar ke sepertiga bagian bawah vagina, mungkin telah menyebar ke dinding panggul, dan/atau telah menyebabkan ginjal tidak berfungsi
- Stadium IV: kanker serviks telah menyebar ke kandung kemih, rektum, atau bagian lain dari tubuh (paru-paru, tulang, liver, dll)
FIGO
|
Deskripsi
|
TNM
|
|
Tumor primer tidak dapat diakses
|
T
x
|
|
Tidak ada bukti tumor primer
|
T
0
|
0
|
Karsinoma
In Situ ( KIS)
|
T
is
|
I
|
Karsinoma terbatas serviks
|
T
1
|
I
a
|
Karsinoma hanya dapat didiagnosis secara mikroskopik
|
T
1 a
|
I
a1
|
Invasi stroma dalamnya <3 mm dan lebarnya < 7 mm
|
T
1 a1
|
I
a2
|
Invasi stroma dalamnya 3-5 mm dan lebarnya < 7 mm
|
T
1 a2
|
I
b1
|
Secara
klinis lesi < 4 cm
|
T
1 b1
|
I
b2
|
Secara
klinis lesi > 4 cm
|
T
1 b2
|
II
|
Proses
keganasan telah keluar dari serviks dan menjalar 2/3 bagian atas vagina dan
parametrium, tetapi tidak sampai dinding panggul
|
T
2
|
II
a
|
Penyebaran
hanya ke vagina, parametrium masih bebas dari infitrat tumor
|
T
2a
|
II
b
|
Penyebaran
ke parametrum
|
T
2b
|
III
|
Tumor menginvasi sampai dinding pelvis dan atau
menginfiltrasi dampai 1/3 distal vagina dan atau menyebabkan hidronefrosis
atau gagal ginjal
|
T
3
|
III
a
|
Penyebaran
sampai 1/3 bagian distal vagina
|
T
3a
|
III
b
|
Penyebaran sudah sampai dinding panggul,
|
T
3b
|
IV
|
Proses
keganasan telah keluar dari panggul kecil dan melibatkan mokusa rektum dan
atau vesika urinaria atau telah bermetastasi keluar panggul ketempat yang
jauh
|
T
4
|
IV
a
|
Proses
sudah sampai mukosa rektum dan atau vesika urinaria atau sudah keluar dari
pangul kecil, metastasi jauh belum terjadi
|
T
4a
|
IV
b
|
Telah
terjadi metastasi jauh
|
T
4b
|
Tabel 1. Staging
Karsinoma Serviks Menurut FIGO1
5 comments:
oooo
o itu bulet manter. wkwk
iziin copy inii...
tmn apaan ?
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